Volume 39 No 6  Cover Story

Cerebral amyloid angiopathy is characterized by the deposition of amyloid β-protein in the wall of small to medium sized arteries of the leptomeninges and cerebral cortex. While often asymptomatic, cerebral amyloid angiopathy can develop into intracerebral hemorrhage facilitated by arterial hypertension. The thickened small artery is densely stained with Congo-red in surgical specimen.