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Journal of Korean Neurosurgical Society 2001;30(2): 221-226.
A Case of Gliosarcoma Associated with Neurofibromatosis Type 1.
Dae Won Kim, Jong Tae Park, Jong Moon Kim, Tae Young Kim
Department of Neurosurgery, School of Medicine, Wonkwang University, Iksan, Korea.
ABSTRACT
A rare case of gliosarcoma with neurofibromatosis typeI is presented. The patient was a 33-year-old woman who had headache and vomiting for one week. Multiple neurofibromas over her whole body with many cafe-au-lait spots were present since childhood. At admission, she had no focal neurological deficit and ophthalmologic examination revealed bilateral Lisch nodules. Brain CT and MRI revealed a heterogeneously enhancing mass in the left fronto-parietal region with marked peritumoral edema and mass effect. The tumor was removed gross totally and a gliosarcoma was diagnosed histopathologically. Post operative course was uneventful with resolution of symptom, followed by radiotherapy with 60 Gy. A brief overview is given of this rare case together with the pertinent literature.
Key Words: Gliosarcoma; Neurofibromatosis type I
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