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Journal of Korean Neurosurgical Society 2001;30(1): 99-104.
Deep Cerebral Venous Thrombosis: Successful Treatment by Systemic Urokinase Followed by Heparin: Case Report.
Jae Hyo Park, Ji Ho Yang, Do Sung Yoo, Kyoung Suok Cho, Pil Woo Huh, Seong Oh Kwon, Dal Soo Kim, Joon Ki Kang
1Department of Neurosurgery, Uijongbu St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Uijongbu, Korea.
2Department of Neurosurgery, College of Medicine, Pochon CHA University, Korea.
ABSTRACT
We present two cases of deep cerebral venous thrombosis(DCVT) with the totally occluded straight sinus. A 42-year-old female received with altered mentality . She has taken antihistamine for six years to treat the paranasal sinusitis. Another 34-year-old female who used the oral contraceptive for 11 months presented with acute behavior change . Both of these patients were diagnosed by computed tomography(CT), magnetic resonance(MR) imaging, and cerebral angiography. They were fully recovered with systemic urokinase thrombolysis followed by heparin therapy. We report that the intravenous thrombolysis was potentially effective management strategy in our cases of DCVT with the totally occluded straight sinus.
Key Words: Deep cerebral venous thrombosis; Urokinase; Heparin; Thrombolysis
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