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Journal of Korean Neurosurgical Society 1999;28(8): 1194-1198. |
| Epithelioid Hemangioendothelioma. |
| Sung Rok Han, Chong Oon Park, Dong Keun Hyun, Young Soo Ha |
| Department of Neurosurgery, Inha Hospital, College of Medicine, Inha University, Kyunggido, Korea. |
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| ABSTRACT |
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Epithelioid hemangioendothelioma is a rare vascular neoplasm characterized by epithelioid tumor cells and borderline biologic behavior. We present a case of grade III malignant epithelioid hemangioendothelioma of the skull and brain parenchyme in a 58-year-old female. The tumor consisted of loose aggregates of epithelioid cells with a focal small nest pattern and tumor cells displayed frequent intracytoplasmic vacuoles and contained areas with significant atypia and mitotic activity(more than 2/10 HPF).
Immunohistochemically, the tumor cells showed positive staining for facor VIII-RGA and vimentin. Radiological and histopathologic characteristics of this tumor with a review of pertinent literature is presented. |
| Key Words:
Epithelioid hemangioendothelioma; Computed tomography; Magnetic resonance imaging; Histopathology; Immunohistochemistry |
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