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Journal of Korean Neurosurgical Society 1996;25(11): 2354-2359. |
| Miliary Tuberculosis Involving the Central Nervous System. |
| Tae Whoan Lee, Hun Joo Kim, Chul Hu, Yong Pyo Han, Soon Ki Hong, Jhin Soo Pyen, Myung Soon Kim, Mee Yon Cho, Yoon Mee Kim |
1Department of Neurosurgery, Wonju College of Medicine, Yonsei University, Wonju, Korea.
2Department of Diagnostic Radiology, Wonju College of Medicine, Yonsei University, Wonju, Korea.
3Department of Pathology, Wonju College of Medicine, Yonsei University, Wonju, Korea. |
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| ABSTRACT |
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In recent times, central nervous system(CNS) tuberculosis has been rare and the prevalence of the focal form, the tuberculoma, varies from 1 per 20 to 1 per 1000. CNS tuberculosis occurs as a result of hematogenous sparead from a primary focus, mostly pulmonary tuberculosis. It can be diffuse exudative leptomeningitis or a localized tuberculoma; the former is more common. We report a case of military cerebral tuberculosis in a 24-year-old female who had been having headaches for 4 months. Magnetic resonance imaging showed numerous small round Gadolinium-enhanced supratentorial and infratentorial lesions scattered throughtout the brain. Histologic examination confirmed well-defined tuberculous granulomas with central caseous necrosis in open biopsy, containing several acid-fast bacilli, the patient was treated with isoniazid, rifampin, ethambutol, pyrazinamide in combination with prednisolone. |
| Key Words:
Miliary cerebral tuberculosis; Small enhancing nodule; Mycobacterium tuberculosis |
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