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Journal of Korean Neurosurgical Society 1996;25(5): 1063-1068.
Central Neurocytoma: A Case Report.
Moon Chul Kim, Moon Sik Park, Sang Pyung Lee, Yong Jin Kim, Ki Whan Choi, Hyung Tae Yeo, Jung Kil Rhee
1Department of Neurosurgery, Taegu Hyosung Catholic University Hospital, Taegu, Korea.
2Department of Pathology, Taegu Hyosung Catholic University Hospital, Taegu, Korea.
ABSTRACT
A rare case of intraventricular central neurocytoma in 17-year-old male is reported. The patient had diffuse headache and diplopia. Radiologic findings displayed obstructive hydrocephalus and a large, well-demarcated intraventricular mass lesion obstructing the foramen of Monroe. The tumor arouse from the splenium of corpus callosum. It was removed successfully using two different approaches after extraventricular drainage of the cerebrospinal fluid(CSF). Histologically, the tumor showed pathological features as that of oligodengroglioma on the light microscope. In immunohistochemical examination, glial fibrillary acidic protein(GFAP) was negative and synaptophysin, positive. Numerous neurosecretory granules were found and no typical synapsis was noticed on the electron microscope. No shunt operation was needed. Postoperative radiotherapy or chemotherapy was not performed and no tumor recurrence was detected during the one year follow-up period. We present the case together with a review of the literatures.
Key Words: Intraventricular neurocytoma; GFAP; Synaptophysin; Neurosecretary granules
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