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Journal of Korean Neurosurgical Society 1995;24(12): 1594-1599.
Surgical Experience of Intracranial Aneurysm in a Patient with Polycystic Kidney: Case Report.
Won Hur, Hwa Sung Park, Sang Yong Kim, Dong Yul Lee
Department of Neurosurgery, Wallace Memorial Baptist Hospital, Pusan, Korea.
ABSTRACT
Rupture of cerebral aneurysm is a significant cause of morbidity and mortality in patients with polycystic kidney. Although many authors have emphasized the relationship between these two diseases, the exact pathogenesis has yet to be identified yet. Recently a number of authors have emphasized the defect of chromosome 16 as the basis of pathogenesis of these disease. We have treated surgically a case of P2-3 junction aneurysm in a 44 year-old male with bilateral polycystic kidneys. While abdominal ultrasonograph had revealed multiple microcysts of the liver, four vessel angiographies futher revealed marked arteriosclerotic changes of cerebral arteries. The aneurysmal neck was successfully clipped through subtemporal approach resulting in good outcome. The above mentioned cases of cerebral aneurysm with polycystic kidney will be discussed with respect to its pathogenesis and treatment modality along with literature review.
Key Words: Polycystic kidney; Intracranial aneurysm
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