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Journal of Korean Neurosurgical Society 1995;24(10): 1219-1225.
Clinical Experience of Gamma Knife Rediosurgery for Acoustic Neurinomas.
Yang Kwon, Dong Jun Lee, Jung Kyo Lee, Byung Duk Kwun, Choong Jin Whang
Department of Neurological Surgery, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea.
ABSTRACT
Microsurgical tumor removal is the treatment of choice to relieve the mass effect for the treatment of acoustic neurinoma patients. Gamma knife radiosurgery is another treatment option for patients with tumor size of less than approximately 4cm. Between May, 1990 and March, 1994, 55 tumor lesions from 50 patients were treated with gamma knife radiosurgery at Asan Medical Center. Following microsurgery, 20 patients underwent gamma knife radiosurgery for tumors not removed surgically. The remaining 30 patients underwent gamma knife radiosurgery alone. For an average follow-up period of 26 months(ranging from 6 to 45 months), 37 lesions out of 39 lesions responded, giving a tumor growth control rate of 94.9%. Facial neuropathy and trigeminal neuropathy were noted in 8% and 6%, respectively. According to these results, it is suggested that gamma knife radiosurgery in an effective altrnative therapeutic modality for the management of small to moderate sized acoustic neurinomas.
Key Words: Acoustic neurinoma; Stereotactic radiosurgery; Tumor control rate; Facial neuropathy; Trigeminal neuropathy
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