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Journal of Korean Neurosurgical Society 1989;18(6): 926-930.
A Clinical Analysis of Delayed Radiation Necrosis of the Brain.
Jae Gon Moon, Seung Kon Huh, Joong Uhn Choi, Sang Sup Chung, Kyu Chang Lee, Dong Ik Kim, Jung Ho Suh
1Department of Neurosurgery, College of Medicine, Yonsei University, Seoul, Korea.
2Department of Radiology, College of Medicine, Yonsei University, Seoul, Korea.
ABSTRACT
Radiotherapy is a standard postoperative treatment for various cerebral neoplasms. Howewr, radiation has the potential to produce severe injury to normal brain tissue in and around the tumor bed. The authors encountered 7 patients with delayed cerebral necrosis. These unacceptable complication prompted us to analyze cases with such a complication particularly in regard to the differential diagnosis between the recurrence of the tumor and radiation necrosis of the brain. This article summarizes factors related to the radiation necrosis, including clinical observations and treatment.
Key Words: Radiation; Brain injury; Steroid
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