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Journal of Korean Neurosurgical Society 1989;18(1): 143-147. |
| Intracerebral Hemorrhage in Newborn Infants Secondary to Vitamin K Deficiency. |
| Sin Jung, Soo Han Kim, Sam Suk Kang |
| Department of Neurosurgery, Chonnam University Medical School, Kwangju, Korea. |
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| ABSTRACT |
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Intracerebral hemorrhage secondary to vitamin K deficiency is presented in three newborn infants: 4 days, 28 days and 21 days of age respectively. After the administration of vitamin K(5-10 mg) either intravenously or intramusculary, prolonged prothrombin time(PT) and partial thromboplastin time(PTT) were corrected promptly. Vitamin K dependent coagulation factor deficiency due to vitamin K deficiency is accounted for the pathogenesis of hemorrhage. The possible causes of vitamin K deficiency, diagnostic methods and treatment of this disease entity are reviewed. Neurosurgeons as well as pediatricians should remain alert for the development of intracerebral hemorrhage caused by vitamin K deficiency in neonatal period. |
| Key Words:
Coagulation factor; Intracerebral hemorrhage; Prothrombin time; Partial thromboplastin time; Vitamin K deficiency |
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