Spontaneous Intracranial Hemorrhage Caused by Brain Tumor.

Lee, Sang Hyung; Wang, Kyu Chang; Kim, Jong Soo; Lee, Sun Ho; Kim, Hyun Jip; Cho, Byung Kyu; Han, Dae Hee; Sim, Bo Sung; Choi, Kil Soo

Original Article

Journal of Korean Neurosurgical Society 1988;17(5): 1053-1064.

Sang Hyung Lee, Kyu Chang Wang, Jong Soo Kim, Sun Ho Lee, Hyun Jip Kim, Byung Kyu Cho, Dae Hee Han, Bo Sung Sim, Kil Soo Choi

Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea.

ABSTRACT

919 consecutive brain tumor cases and 665 consecutive spontaneous intracranial hemorrhage cases were reviewed for the analysis of cases in which spontaneous intracranial hemorrhage caused by brain tumor was confirmed with gross operative findings. Authors analyzed their incidence, patients' demography, tumor histology, clinical symptoms and signs, predisposing factor, tumor vascularity, type of hemorrhage, relations between the clinical symptoms and signs and the type of hemorrhage, relations between the location of tumor and the type of hemorrhage and the outcome of treatment. The conclusions are as follow; 1) The proportion of the hemorrhage caused by brain tumor to the total spontaneous intracranial hemorrhage was 5.1%(34/665). 2) The proportion of the spontaneous intracranial hemorrhage caused by brain tumor to the total brain tumor was 3.7%(34/919) and the proportion of that excluding pituitary adenoma was 2.5%(18/729). 3) Compared with the other brain tumors, oligodendroglioma and pituitary adenoma had significant tendency of hemorrhage(p<0.05, p<0.01, respectively) and meningioma had a significantly low incidence of hemorrhage(p<0.05). 4) The hemorrhage brought about major symptoms in 13 cases(72%), minor symptoms in 2 cases(11%). These cases showed no symptoms related to the hemorrhage. 5) Among the 18 cases of spontaneous intracranial hemorrhage caused by brain tumor, one case with the major attack died of postoperative pneumonia. There were additional 2 motalities which were not related to the preoperative hemorrhage. And most of the symptoms associated with the preoperative hemorrhage stabilized or improved with operative treatment.

Key Words: Spontaneous intracranial hemorrhage; Brain tumor