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Journal of Korean Neurosurgical Society 1988;17(5): 1029-1034. |
| Diagnosis of Cerebrovascular Disease Using 99mTc-HMPAO SPECT. |
| Do Heum Yoon, Seung Kon Huh, Kyu Chang Lee, Do Yun Lee, Tae Sub Chung |
1Department of Neurosurgery, Yonsei University, College of Medicine, Seoul, Korea.
2Department of Radiology, Yonsei University, College of Medicine, Seoul, Korea. |
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| ABSTRACT |
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A new radiopharmaceutical, technetium-99m hexamethylpropyleneamine oxime(99mTc-HMPAO), has been reported to cross the blood-brain-barrier and to distribute in brain in proportion to regional blood flow. Measurement of cerebral blood flow with single photon emixxion computed tomography(SPECT) was performed using 99mTc-HMPO in 46 patients and clinical analysis was done. Decreased regional cerebral perfusion was observed in 41 cases. Moreover eight cases of them who had normal X-ray C-T scan revealed positive finding on SPECT. We porpose that 99mTc-HMPAO SPECT seems to be a useful diagnostic method for evaluation of ischemic cerebral lesions. |
| Key Words:
99mTc-HMPAO; SPECT; rCBF; Cerebrovascular disease |
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