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Journal of Korean Neurosurgical Society 1987;16(4): 1221-1226.
Nelson's Syndrome: A Case Report.
Yang Kwon, Hee Won Jung, Je G Chi, Kil Soo Choi
1Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea.
2Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea.
ABSTRACT
A case of Nelson's syndrome in 23 year-old female, developing 6 years after bilateral adrenalectomy for Cushing's syndrome, is reported. Presenting symptoms were headache and hyperpigmentation of the skin and mucous membrane. Serum ACTH level was markedly elebated above 1000 pg/ml, but serum cortisol level diminished markedly. Transsphenoidal approach (TSA) with removal of gushing out hematoma and tumor underwent. Postoperatively, headache subsided and hyperpigmentation of the skin markedly improved.
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