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Journal of Korean Neurosurgical Society 1987;16(4): 1221-1226. |
Nelson's Syndrome: A Case Report. |
Yang Kwon, Hee Won Jung, Je G Chi, Kil Soo Choi |
1Department of Neurosurgery, College of Medicine, Seoul National University, Seoul, Korea. 2Department of Pathology, College of Medicine, Seoul National University, Seoul, Korea. |
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ABSTRACT |
A case of Nelson's syndrome in 23 year-old female, developing 6 years after bilateral adrenalectomy for Cushing's syndrome, is reported. Presenting symptoms were headache and hyperpigmentation of the skin and mucous membrane. Serum ACTH level was markedly elebated above 1000 pg/ml, but serum cortisol level diminished markedly.
Transsphenoidal approach (TSA) with removal of gushing out hematoma and tumor underwent. Postoperatively, headache subsided and hyperpigmentation of the skin markedly improved. |
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