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Journal of Korean Neurosurgical Society 1982;11(3): 299-302. |
| Treatment of Parkinson's Disease with Bromocriptine. |
| Chang Rak Choi, Yong Park, Ki Won Sung, Chun Chang Lee |
| CNS & Pain Management Institute St. Paul's Hospital Catholic Medical College, Seoul, Korea. |
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| ABSTRACT |
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Bromocriptine(15-100 mg/day) alone and with L-dopa were studied for 10-30 months on 22 patients with Parkinson's disease. Patients who had never received L-dopa treatment either because it was never attempted or of intolerance from the onset was placed under Bromocriptine. The responses of patients were excellent. Its antiparkinsonism activity in comparable with that of L-dopa with the advantage of reducing the unwanted side effects of L-dopa during the reduction of its dosage, for patients who have been taking the drug. However, this decrease of dosage should be effected gradually, while the dose of Bromocriptine in being increased. Bromocriptine did not treat the "on-off" effects of L-dopa but reduced the cardiac complications, painful contractions and dyskinesia. |
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