T-Lymphocyte Fluctuation in Patients with Primary Intracranial Tumors. |
Won Mann Moon, Seung Lae Kim, Tai Ho Chung |
1Department of Neurosurgery, School of Medicine, Kyungpook National University, Daegu, Korea. 2Department of Biochemistry, School of Medicine, Kyungpook National University, Daegu, Korea. |
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ABSTRACT |
To determine the T-cell mediated immunological status in patients with brain tumors, the percentages of active and total T-lymphocytes forming rosettes with sheep erythrocytes, were measured in sixteen patients with primary intracranial tumors;six benign astrocytomas, four glioblastomas, one medulloblastoma, two craniopharyngiomas and three meningiomas. The percentages of active and total T-lymphocytes were significantly decreased in all glioblastomas and two among six astrocytomas, but normal in all meningiomas. |
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