Volume 41 No 4  Cover Story

Photomicrographs showing lymphocytic hypophysitis in a 34-year-old man presented with progressive visual disturbance, headache and decreased libido. Lymphoid cells are diffusely infiltrated into the atrophic pituitary acini in H&E stain (upper). Immunohistochemistry demonstrates the inflammatory cells consisting of mainly CD3-positive T lymphocytes (lower).