Volume 61 No 1  Cover Story

Six weeks following SCI, histological examination revealed a central cavity with peri-lesional regeneration. The lesion cavity extended to over 2 mm rostrally and 2 mm caudally, tapering gradually to cavities affecting the central and dorsal areas of the spinal cord gray and white matter. Measurements of the average area of lesion cavity at the injury epicenter and adjacent sections at an interval of 2 mm up to 4 mm rostrally and caudally. A : SCI-vehicle group. B : SCI-curcumin group. C : Histogram (C) showing the cavitation volume of the spinal cord lesion in both groups. *p <0.05, compared with the respective vehicle control. R : rostral, C : caudal, SCI : spinal cord injury.