The effect of genetically modified Lactobacillus Plantarum (LP) carrying Bone Morphogenic Protein (BMP) 2 gene on animal osteoporosis model. On hematoxylin and eosin (H&E, upper row) and Masson’s trichrome staining (lower row) of tibia, there are more preservation of the trabecular formation in the ovariectomy induced osteoporosis (OVX) in LP with BMP group (far right column) compared to the OVX (second from left) and OVX/LP group (third from left). Far left column is control, sham group.