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Journal of Korean Neurosurgical Society 2010;47(4): 295-297.
doi: https://doi.org/10.3340/jkns.2010.47.4.295
Candida Parapsilosis Spondylodiscitis after Lumbar Discectomy.
Kyungil Cho, Sun Ho Lee, Eun Sang Kim, Whan Eoh
Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. sobotta72@hotmail.com
ABSTRACT
Candida is a relatively rare cause of spinal infections that commonly affects immunocompromised patients. A 70-year-old woman, who underwent a lumbar discectomy on L5-S1 two months earlier, was admitted to our department complaining of persistent back and leg pain. Magnetic resonance imaging showed irregular enhancing mass lesion in L5-S1 intervertebral space, suggest of pyogenic discitis with epidural abscess. The surgery was performed via retroperitoneal approach and the infected material at L5-S1 intervertebral space was removed. The histological examination of the specimen revealed chronic inflammation involving the bone and soft tissue, and a culture of the excised material was positive for Candida parapsilosis. The patient received intravenous fluconazole for 4 weeks after surgery and oral fluconazole 400 mg/day for 3 months after surgery. The patient made a full recovery with no symptoms 6 months after surgery. We present a rare case of spondylodiscitis after a lumbar discectomy due to Candida parapsilosis and discuss treatment option with a review of the literatures.
Key Words: Spondylodiscitis; Candida; Fungal infection; Vertebra; Osteomyelitis
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