| Home | E-Submission | Sitemap | Editorial Office |  
top_img
Journal of Korean Neurosurgical Society 2006;39(4): 300-302.
"Brain Stunning" Atypical Feature of tPA Thrombolysis Following Aneurysm Embolization.
Min Woo Park, Hyeong Joong Yi, Rishi Gupta, Michael B Horowitz
1Department of Neurosurgery, Hanyang University Medical center, Seoul, Korea. hjyi8499@hanyang.ac.kr
2Center for Endovascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
ABSTRACT
"Stunning" represents prolonged contractile depression of any muscular component after alleviation of severe ischemia, as shown in reperfusion following acute myocardial ischemia or ischemic stroke. Clinically, it presents with no or delayed recovery past to thrombolytic therapy but its pathogenic mechanism is not fully uncovered yet. We describe a unique case of a 63-year-old woman, who was undertaken endovascular coiling for the aneurysms, deteriorated several hours later without known cause, and showed delayed clinical improvement over the next 3 days following thrombolysis. Immediate post-thrombolysis magnetic resonance imaging scan showed no apparent abnormality except for high signal intensity within the corresponding hemisphere. Reversible, but delayed nature of "brain stunning" can be explained by these images and it seems to be caused by a certain type of reperfusion injury.
Key Words: Acute ischemic stroke; Endovascular coiling; Magnetic resonance imaging; (Brain) Stunning; Thrombolytic therapy
TOOLS
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Share:      
METRICS
1,274
View
18
Download
Related article
Editorial Office
1F, 18, Heolleung-ro 569-gil, Gangnam-gu, Seoul, Republic of Korea
TEL: +82-2-525-7552   FAX: +82-2-525-7554   E-mail: office@jkns.or.kr
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © Korean Neurosurgical Society.                 Developed in M2PI
Close layer