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Journal of Korean Neurosurgical Society 2006;39(2): 148-151. |
| Brain Metastasis from Dermatofibrosarcoma Protuberans. |
| Wook Ha Kim, Chul Kee Park, Dong Gyu Kim, Hee Won Jung |
| Department of Neurosurgery, Seoul National University College of Medicine, Clinical Research Institute, Seoul, Korea. hwnjung@snu.ac.kr |
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| ABSTRACT |
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Dermatofibrosarcoma protuberans(DFSP) is an uncommon fibrohistiocytic tumor characterized by aggressive local invasion and consequent local recurrence rather than distant metastasis. We present a case of a 51-year-old male patient with a typical cutaneous DFSP, which showed local recurrences and distant metastasis to the central nervous system(CNS) and the lung after 15 years from the initial diagnosis. CNS metastatic lesions recurred in 5 months after surgical resection of the first CNS lesion. These metastatic tumors were treated by open surgery and gamma-knife radiosurgery. Despite continuous medication of oral chemotherapeutic agent, the patient died during 1-year follow-up period. |
| Key Words:
Dermatofibrosarcoma protuberans; Brain metastasis |
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