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Journal of Korean Neurosurgical Society 2005;37(4): 296-299.
Primary Central Nervous System Lymphoma in Organ Recipient.
Ki Sun Hong, Sang Dae Kim, Dong Jun Lim, Jung Yul Park
Department of Neurosurgery, Korea University Medical Center, Ansan Hospital, Ansan, Korea. neuron19@korea.ac.kr
ABSTRACT
We report a case of primary central nervous system(CNS) lymphoma in an organ recipient. A 33-years-old man who underwent a renal transplantation 3years previously presented with headache and vomiting. In Brain computed tomography scans and magnetic resonance images showed multiple periventricular cystic rim enhancing masses. Pathologic diagnosis by stereotactic biopsy revealed malignant non-Hodgkins B-cell lymphoma. After pathologic confirmation, methotrexate chemotherapy and whole brain radiation therapy were done. Having experienced such a case, the authors strongly recommend to add primary CNS lymphoma as one of the differential diagnoses to brain abscess, metastatic brain tumor and glioblastoma multiforme in cases of multiple ring enhancing periventricular lesions of immunocompromised patient or organ recipient.
Key Words: Primary central nervous system lymphoma; Organ recipient; Periventricular lesion; Ring enhancement
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