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Journal of Korean Neurosurgical Society 1998;27(11): 1611-1614. |
| Lymphocytic Hypophysitis: A Cases Report. |
| Dong Jun Lim, Yong Gu Chung, Hoon Kap Lee, Ki Chan Lee, Jung Keun Suh |
| Department of Neurosurgery, College of Medicine, Korea University, Seoul, Korea. |
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| ABSTRACT |
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Lymphocytic hypophysitis is a rare inflammatory disease of the pituitary gland that is being recognized increasingly as a cause of hypopituitarism. Lymphocytic hypophysitis is due to autoimmune pituitary destruction and often occurs with other autoimmune diseases. We report a rare case of lymphocytic hyphophisitis in a 21-year old woman, who suffered from systemic lupus erythematosus(SLE), presenting with intermittent headache for 2 months. Magnetic Resonance Imaging with a contrast medium revealed expanding sellar mass with hemorrhage. The patient underwent transsphenoidal surgery with a provisional diagnosis of pituitary adenoma.
Histological examination revealed evidence of lymphocytic hypophysitis. We report a case of lymphocytic hypophysitis in nonpregnant women who suffered from SLE, an immunologically mediated multisystem disease. |
| Key Words:
Lymphocytic hypophysitis; Pituitary tumor; SLE; Systemic lupus erythematosus |
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