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Journal of Korean Neurosurgical Society 1998;27(6): 831-836. |
Cellular Schwannoma of the Cervical Spine in an Infant: A Case Report. |
Oon Ki Baek, Ki Uk Kim, Seo Hee Rha, Jong Geun Kim, Hyu Jin Choi, Hyung Dong Kim |
1Department of Neurosurgery, College of Medicine, Dong-A University, Pusan, Korea. 2Department of Pathology, College of Medicine, Dong-A University, Pusan, Korea. |
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ABSTRACT |
Cellular schwannoma is a very rare benign tumor involving peripheral nerves, mimicking malignant nerve sheath tumor in histological appearance. It is a clinico-pathological variant of benign schwannoma characterized by a high cellularity, increased mitotic figures and occasional presence of bone destruction. A 6-month-old female patient was admitted with progressive quadriparesis. Magnetic resonance imaging of the cervical spine showed a well-enhancing extramedullary mass on the C4 to C6 area.
Total laminectomy was performed on C4-7, and intradural extramedullary tumor was removed. Histologically, the tumor was composed of proliferated spindle cells. Most of the tumor was composed of Antoni A area with hypercellular spindle cells arranged in fascicular pattern. The tumor cells showed mild atypism with mitotic figure upto 4/10HPF and diffuse, strong S-100 protein immunostaining. The patient was improved postoperatively. |
Key Words:
Cellular schwannoma; Spinal cord tumor; Infant |
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