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Journal of Korean Neurosurgical Society 1990;19(5): 646-653.
Stereotatic Interstitial Brachytheraoy with Iridium-192 in the Treatment of Brain Tumors-Report of Intial Experience.
Jong Hyun Kim, Seong Yul Yoo
1Department of Neurosurgery, Korea Cancer Center Hospital, Seoul, Korea.
2Department of Therapeutic Radiology, Korea Cancer Center Hospital, Seoul, Korea.
ABSTRACT
Five patients with brain tumors have been treated with an afterloaded removable Iridium-192 interstitial brachytherapy using Brown-Roberts-Wells stereotactic system. There were two cases of glioblastoma multiforme, one case of recurrent glioblastoma multiforme, one case of recurrent metastatic brain tumor and one case of recurrent astrocytoma grade II. The patients were treated by combination of surgery or stereotactic biopsy and external radiation previously. Tumor doses ranging from 4100 to 8600 cGy were delivered to these patients. There was no death and 4 patients showed definite tumor regression 3 months following interstitial brachytherapy. The method was safe and appeared to be effective madality to achieve local control of brain tumors.
Key Words: Brain tumor; Stereotactic interstitial brachytherapy; Iridium-192
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