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Journal of Korean Neurosurgical Society 1986;15(4): 779-786. |
| Effect of Pinealectomy on the Renin-Angiotensin System in Sprague-Dawley Rats. |
| Yeon Chang Moon, Won Sun Baek, Jong Moon Kim |
| Department of Neurosurgery, College of Medicine, Won Kwang University, Chollabuk-do, Korea. |
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| ABSTRACT |
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Experiments were performed to investigate the effects of pinealectomy on the renin-angiotensin system in Sprague-Dawley rats. The results obtained were as follows.
1) There was no differences of systolic blood pressure, heart rate, water intake, and plasma electrolytes between pinealectomized and sham-operated rats. 2) Renin activity in plasma and pituitary gland did not differ in two experimental groups. 3) The pituitary gland contained the renin activity of about 50pg AI/hr/mg of wet weight. The results suggest that the pineal gland has no correlation with cardiovascular and renin-angiotensin system. |
| Key Words:
Renin in pineal gland; Angiotensin; Renin-angiotensin system; Cardiovascular system; Pinealectomy |
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