| De Novo Aneurysm after Treatment of Glioblastoma. |
| Wan Soo Yoon, Kwan Sung Lee, Sin Soo Jeun, Yong Kil Hong |
1Department of Neurosurgery, Incheon St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Incheon, Korea.
2Department of Neurosurgery, Seoul St. Mary's Hospital, The Catholic University of Korea, College of Medicine, Seoul, Korea. hongyk@catholic.ac.kr |
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| ABSTRACT |
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A rare case of spontaneous subarachnoid hemorrhage from newly developed cerebral aneurysm in glioblastoma patient is presented. A 57-year-old man was presented with headache and memory impairment. On the magnetic resonance image and the magnetic resonance angiography, a large enhancing mass was found at right frontal subcortex and intracranial aneurysm was not found. The mass was removed subtotally and revealed as glioblastoma. He took concurrent PCV chemotherapy and radiation therapy, but the mass recurred one month later after radiotherapy. He was then treated with temozolomide for 7 cycles. Three months after the completion of temozolomide therapy, he suffered from a subarachnoid hemorrhage due to a rupture of a small de novo aneurysm at distal anterior cerebral artery. He underwent an aneurysm clipping and discharged without neurologic complication. |
| Key Words:
Glioblastoma; Intracranial aneurysm; Subarachnoid hemorrhage; Radiation therapy; Chemotherapy |
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