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Journal of Korean Neurosurgical Society > Volume 5(1); 1976 > Article
Journal of Korean Neurosurgical Society 1976;5(1): 21-24.
Effect of Ginseng Extract on Blood Pressure and Intracranial Pressure in Cats.
Kwang Myung Kim, Hwan Yung Chung
Department of Neurosurgery, Hanyang University School of Medicine, Seoul, Korea.
There are two contradictive opinions of the therapeutic administration of Ginseng in the conditions of cerebrovascular accident and/or hypertensive heart diseases. This experimental study was performed to observe the effects of the Ginseng extract on the blood pressure(BP) and intracranial pressure(ICP) at the same time. Seven mongrel cats were used. ICP was measured with epidural ballon and pressure transducer, and BP with intraarterial catheter via female routs. Both were continuously recorded by polygrapher. 1. In a normal condition, a single intravenous injection of Ginseng 100mg/kg induced immediate reduction of BP for 30~45 second. Intracranial pressure, however, showed delayed elevation for 50~60 second. 2. Even in a condition of increased ICP or induced cardiac hypertension, the results were the same as in above-described normal condition.
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